In Ekundina et al., study, the mean percentage reactivity of msh2 in normal, colonic polyps, and colorectal carcinoma was 43.2%, 56.6%, and 90.1% respectively, while the mean percentage reactivity for msh6 was 40.5%, 56.2% and 92% respectively [32]. The gene discussed is MSH2; the disease is colorectal carcinoma.