Galectin-8 binding partners were identified in murine macrophages during intracellular bacterial infection by IP-LC/MS, including autophagy-related proteins such as TAX1BP1 and ubiquitin, and lysosomal proteins and membrane trafficking proteins, including Rab7 and Rab14 (Bell et al, 2021). Here, TAX1BP1 is linked to bacterial infectious disease.