SIX4 and nonpapillary renal cell carcinoma: In addition, the study found that 7 specific genes (ARHGAP42, BTG2, DUSP1, PCDHA12, TAL1, TGFBR3, and SIX4) and 6 microRNAs (hsa-miR-101-3p, hsa-miR-193a-3p, hsa-miR-200a-5p, hsa-miR-214-3p, hsa-miR-221-3p, and hsa-miR-223-3p) showed abnormal activity in ccRCC.