Previous studies have suggested that CCL11 gene polymorphisms might be involved in the development of AD by contributing to a functional dysregulation of CCL11 production in vivo.[27,43] In our study, we found that the CC genotypes of CCL11 − 426C/T, CCL11 − 384A/G and CCL11 − 67G/A were not associated with an increased risk of AD in any of the models. Here, CCL11 is linked to Alzheimer disease.