LGI3 and cancer: More recent studies have proposed that LGI3 may participate in the cytokine network in various cancers[14,16,17] and that the expression levels of LGI3 could have potentially prognostic roles in brain, lung, and colorectal cancers.[16–18] In this study, integrative analyses of gene expression, gene product networks, and patient cohorts were employed to present evidence for the potential prognostic role of LGI3 in pancreatic adenocarcinoma (PAC).