HSPD1 and inflammatory bowel disease: Although heterogeneity was detected in the analysis of IBD (IIBDGC source) versus H. pylori GroEL antibody levels (MR-Egger, Qp = 0.038; IVW, Qp = 0.043), because we chose the IVW of the random-effects model for the MR analysis method, the results of the study are still reliable.[38] We utilized the MR-PRESSO method to identify the horizontal polytropy.