The results showed that compared with the rAd-blank infection, the rAd-Rep, rAd-Cap, or rAd-ORF3 infections all did not significantly affect the expression of 38 kDa pNPM1, while the rAd-Cap infection, but not the rAd-Rep or rAd-ORF3 infections, significantly upregulated the SUMOylated pNPM1 expression (the bands above 250 kDa) (Fig 6A). This evidence concerns the gene ASZ1 and infection.