Compared to the pan-cancer inhibitors I-BET151 [inhibits the bromodomain of Bromodomain and Extra-Terminal motif (BET)] (36) and JQ1 (blocks BRD4 bromodomain) (10), we observed several known leukemia-targeting compounds (EPZ-5676, OICR-9429, A-485, and A-366) (37–40) within the 19 MV4-11 selective inhibitors (detailed in fig. The gene discussed is BRD4; the disease is leukemia.