On the basis of these observations, we focused on the gene loci with reduced H3K9ac [chromatin immunoprecipitation sequencing (ChIP-seq)] and expression (RNA-seq) levels in the sgSgf29 transduced MLL-AF9 leukemia and identified 279 Sgf29-regulated genes (Fig. 4F and data S5). This evidence concerns the gene KMT2A and leukemia.