INS and Hypoglycemia: Although we found disease duration, time in CSII therapy, variability of infusion rate, and basal insulin daily dose (U/kg) factors added to the regression models were not predictors of asymptomatic hypoglycemia in our sample, one could be suggest that the higher incidence of asymptomatic hypoglycemia and unawareness of hypoglycemia in patients with more than 4 BRs could be related to the longer disease duration, a known risk factor for that, but our study did not verify this (21).