While we have identified multiple bacterial species that are capable of eliciting cytotoxic tau and Aβ42 production, future studies will examine whether other causes of pneumonia, including, but not limited to, viruses (i.e., influenza and SARS-CoV2), fungi (e.g., Coccidioidomycosis), and bacterial causes of community-acquired (e.g., Streptococcus pneumoniae) and atypical pneumonias (e.g., Mycoplasma pneumoniae) increase cytotoxic tau and Aβ42. Here, MAPT is linked to susceptibility to pneumonia measurement.