NFE2L2 and Parkinson disease: In contrast, an efficient Nrf2 nuclear translocation has been reported in PD postmortem brains, although an inconsistent reduction of Nqo1 has been observed in other models, which could suggest that even if Nrf2 is being translocated, the expression of its target genes might remain altered in PD (Ramsey et al. 2007; Cook et al. 2011).