In addition, the emerging molecular overlap between these two tumors makes the unequivocal distinction complicated (both conceptually and practically) as recently described “PEComa-like neoplasms characterized by ASPSCR1-TFE3 fusion” can show morphology that more closely resembles PEComa than ASPS (despite their identical pairs of translocation partners) [30]. This evidence concerns the gene TFE3 and neoplasm with perivascular epithelioid cell differentiation.