CYP2B6 and obesity due to melanocortin 4 receptor deficiency: Genes involved in obesity or diabetes were also inversely or directly associated with treated Cyp2b-null mice, including Glycerol-3-phosphate acyltransferase 1 (gpam) and Perilipin-4 (plin4), which are involved in adipose and glycerolipid production [48].