These findings demonstrated that in SH-SY5Y and U-1240 MG cells, AA-inhibited differentiation was mediated through MAPs expression and JAK-STAT signaling, arguing that exposure to AA inhibits cellular differentiation in human neuroblastoma and glioblastoma cells and that downregulation of the JAK-STAT signal pathway may contribute to the understanding of AA-induced neurodegeneration [44]. Here, SOAT1 is linked to glioblastoma.