Recent human and animal studies have revealed new insights into the bone disorders caused by aflatoxicosis, where AFB1 interferes with the expression and function of the vitamin D receptor (VDR), affecting the metabolism of vitamin D2 and D3 into 25-hydroxycholecalciferol (25-OH) and 1,25-dihydroxycholecalciferol (1,25-OHD), resulting in decreased bone quality [21,22,23]. Here, VDR is linked to bone disorder.