CASP3 and neuroblastoma: Exposure to some 1,2-NQs и 1,4-NQs provokes human neuroblastoma cell lines SK-N-SH apoptosis in a ROS-dependent pathway, including DNA damage, mitochondrial dysfunction, and resultant caspase 3 and 9 activation together with GSH decrease, proteasome inactivation and NQO1 upregulation [36].