Indeed, in the same study, the authors investigated the potential role of ghrelin in HAAF using ghrelin knockout mice and ghrelin cell-selective insulin receptor knockout mice and found that the counterregulatory responses (plasma glucagon and adrenaline) were reduced in both strains similar to the C57Bl/6N mice after recurrent hypoglycaemia. The gene discussed is GCG; the disease is Hypoglycemia.