Global gene expression profiling in the adrenal gland to identify variations in the expression of the genes after single and recurrent hypoglycaemia (two episodes per day for 3 days prior to subsequent hypoglycaemia) has highlighted that the expression of the gene that encodes PP2A, a common phosphatase that can dephosphorylate TH, is significantly increased after recurrent hypoglycaemia indicating faster deactivation of TH could occur after recurrent hypoglycaemia [37]. This evidence concerns the gene TH and Hypoglycemia.