CDKN2A and head and neck cancer: In later years, characterized by papers focused on the potential role of HPV in non-oropharyngeal head and neck cancers, some papers started to point to the fact that while a subset of laryngeal cancers indeed overexpressed p16ink4a (range: 4.7% [94]–39.02% [95], according to the papers cited in this review), this did not seem to reflect relevant HPV involvement in the cancerogenic process, but it was still associated with a trend towards better survival [94,96,97,98] and progression-free survival [94,97].