In the study of Duncavage et al., genes required for diagnosis and risk stratification in AML were indicated as ASXL1, BCOR, CEBPA, DDX41, EZH2, FLT3-ITD, FLT3, TKD, IDH1, IDH2, NPM1, RUNX1, SF3B1, SRSF2, STAG2, TP53, U2AF1, and ZRSR2. The gene discussed is IDH1; the disease is acute myeloid leukemia.