As noted above, patients with AOSD are characterized by high levels of CXCR3 ligands—CXCL9, CXCL10, and CXCL11—powerfully recruiting CXCR3-expressing cells (including Tc1 with CXCR3+CCR6– phenotype) into inflamed tissue [29]. The gene discussed is CXCR3; the disease is adult-onset Still disease.