Furthermore, in peripheral blood samples from the AOSD group, the levels of CD8+ T cells were elevated if compared to healthy controls (30.77% (26.44; 39.60) vs. 23.42% (19.55; 28.52), p = 0.010), but these two groups had similar percentages of CD4+ T cells (47.09% (30.05; 57.17) vs. 47.04% (40.65; 47.94), respectively, with p = 0.805) and similar CD4/CD8 ratio (1.53 (0.87; 2.17) vs. 1.77 (1.52; 2.44), respectively, with p = 0.192). This evidence concerns the gene CD8A and adult-onset Still disease.