CXCL9 and adult-onset Still disease: As noted above, patients with AOSD are characterized by high levels of CXCR3 ligands—CXCL9, CXCL10, and CXCL11—powerfully recruiting CXCR3-expressing cells (including Tc1 with CXCR3+CCR6– phenotype) into inflamed tissue [29].