Next, within CD45RA–CD62L– effector memory Tfh cells that were able to leave circulating blood, to migrate to the sites of inflammation and to take part in ectopic lymphoid structure formation [20], we found decreased levels of Tfh2 cells (6.94 (1.57; 11.70) vs. 14.23 (9.89; 18.58) with p = 0.010) and increased levels of DP Tfh cells (31.53 (22.40; 37.80) vs. 18.86 (17.00; 23.48) with p = 0.007) in patients with AOSD vs. healthy controls. This evidence concerns the gene SELL and adult-onset Still disease.