AKT1 and type 2 diabetes mellitus: To proceed to the investigation of mechanisms on UroA actions using T2D model KK-Ay/Ta mice, we finally examined the effect of UroA on GLUT4 translocation to the plasma membrane (PM) from the cytosol as post-plasma membrane (Post PM), induced by the phosphorylation of Akt and AMPK, in the L6 myotubes by Western blot analysis.