HLA-DRB1 and hepatitis B virus infection: For example, Chinese patients exhibit heightened hepatitis risk with HLA B*48 and DRB1*48 genotypes [7], whereas acute hepatitis B patients in the same population have lower occurrences of HLA-DRB1*11:01/11:04 and HLA-DQA1*03:01 compared to those with chronic hepatitis [8].