Thus, in Northern Europe, AIH has been associated with DRB1*03 and DRB1*04 in adult patients [45]; Italian patients express HLA DR4 [46]; while in North America, DRB1*03:01-DQB1*02:01 and DRB1*04:01-DQB1*03:02 haplotypes were more present in AIH patients vs. healthy individuals [47]. The gene discussed is HLA-DRB1; the disease is autoimmune hepatitis.