MLANA and uveal melanoma: The development of uveal melanoma is primarily correlated with specific genetic aberrations including chromosome 3 complete monosomy, 6 disomy, and 8q gain or 8p loss, as well as the expression of the human melanoma black 45 (HMB45) antigen, the S-100 protein, Melan-A (also known as the melanoma antigen recognized by T cells 1/MART-1), melanocyte-inducing transcription factors (MITFs), tyrosinase, vimentin, and sex-determining region Y-Box 10 (SOX10), which were detected in immunohistochemistry [7,8].