The 2019 European League Against Rheumatism (EULAR) and the American College of Rheumatology (ACR) classification of SLE requires an ANA titer of ≥1:80 (Hep-2 Indirect immunofluorescence or equivalent test) as the entry criterion since sensitivity nears 100% [11,12]. Here, BTG3 is linked to systemic lupus erythematosus.