BRCA1 and ovarian carcinoma: Due to the inability to effectively screen for ovarian cancer, global organizations including the American College of Obstetricians and Gynecologists recommend the simultaneous preventive removal of both fallopian tubes and ovaries at the age of 35–40 in the case of BRCA1 mutations and at the age of 40–45 in the case of BRCA2 mutations [103].