However, in the non-metastatic HNSCC group, a significantly higher relative HLA-G mRNA expression was found in patients with tumors in the T4 stage as compared to those with tumors in the T1 and T2 stages (1.480 ± 1.801 vs. 0.2680 ± 0.3137, p = 0.0289, Table 5). Here, HLA-G is linked to head and neck squamous cell carcinoma.