In this regard, a study analyzing frozen human postmortem spinal cord specimens found that individuals who had ALS or multiple sclerosis (MS) presented an increased density of P2X7 receptors in the regions affected by these diseases when compared to healthy individuals, demonstrating the involvement of this receptor in ALS and other neurodegenerative diseases [16]. The gene discussed is P2RX7; the disease is amyotrophic lateral sclerosis.