The most common variant of PCD is ataxic syndrome, associated with the Anti-Yo antibody or Purkinje cell cytoplasmic antibody type 1 (PCA1) [18], which is more frequently associated with breast cancer and gynaecological malignancy (tumours of the ovary, endometrium, and fallopian tube) [2,87,88,89]. This evidence concerns the gene CDR2 and breast cancer.