SLC25A4 and autosomal dominant progressive external ophthalmoplegia: ANT1-related PEO is associated with adPEO and affects the adenine nucleotide translocase type 1 (ANT1) gene, which encodes the translocator responsible for ADP to ATP exchange in the inner mitochondrial membrane and regulates the mitochondrial permeability transition pore that initiates apoptosis [94].