IDH1 and glioblastoma: Figure 1a illustrates a case of newly diagnosed recurrent glioblastoma (IDH1 wild-type, MGMT methylated) on a 6-month surveillance MRI in a 54-year-old man who had undergone gross total resection 6.5 years ago, and completed concurrent radiation and temozolomide followed by six cycles of adjuvant temozolomide.