TNF and infection: Wnt signaling molecules, genes associated with inflammation and infection, such as EBF1, TIMP2, [36,37] COL4A3 [37,38], TNF [39,40,41,42], and the candidate gene for schizophrenia, i.e., ABCA13, have been identified as PTB biomarkers through the multiple target studies, though their mechanisms remain unclear [43,44,45,46].