COL2A1 and cyclic hematopoiesis: The COL2A1 expression on day 7 was significantly higher for SC-200 in CH medium than for 2D controls (p < 0.01), for 2D controls in CH (p < 0.001), for SC-500 in BM (p < 0.01), and for SC-500 in CH culture fluid (p < 0.01).