In BV-2 (murine microglial cells) and SH-SY5Y (human neuroblastoma) cells, the use of maple syrup enriched with phenols decreased the levels of ROS, NOS, and inflammatory mediators such as IL-6, prostaglandin E2 (PGE 2), and tumor necrosis factor α (TNF-α) [62]. This evidence concerns the gene TNF and neuroblastoma.