Such a model could include the generation of murine lymphoma or myeloma cell lines, stably transfected with human BCMA, to be used in syngeneic immunocompetent mice, similar to what has been performed for anti-CD20 antibodies, given that the anti-PDL1 moiety of the bsAb also recognizes murine PDL1 [41,42]. This evidence concerns the gene CD274 and lymphoma.