In another study, a patient with a 20-year history of SLE complicated by stage IV diffuse large B-cell lymphoma was treated with compound CAR-T (cCAR-T) co-expressing anti-BCMA and anti-CD19, targeting both CD19+ memory B cells and BCMA+ plasma cells (Figure 1). This evidence concerns the gene TNFRSF17 and systemic lupus erythematosus.