The cardiovascular effects of cannabis use are not just acute, i.e., cannabis arteritis, cannabis-induced vasospasms, and platelet aggregation, but cannabis use is also hypothesized to be involved in atherosclerosis progression due to the abundance of CB1 and CB2 receptors (cannabinoid receptors) in the pulmonary and cardiovascular systems [17]. This evidence concerns the gene CNR1 and atherosclerosis.