HLA-DRB1 and Ehlers-Danlos syndrome: For example, the DRB1 (*1101) allele is associated with increased risk of sarcoidosis in ADs and EDs [35], whereas DRB1 (*0101), DQB1 (*0501), and DQA1 (*0101) alleles were associated with reduced risk of sarcoidosis in diverse ED populations (UK, Netherlands), and in Japanese subjects [11, 43, 59, 60].