Furthermore, utilizing the same cytokine cocktail employed for NK cell development from CD34+ hematopoietic stem cells in vitro resulted in the predominant differentiation of T cells, suggesting that the ability of inflammatory CLPs to follow a specific developmental program may be determined elsewhere (e.g., bone marrow) and that tumor-derived or tissue stimuli may only be able to partially influence their functional trajectory. The gene discussed is CD34; the disease is neoplasm.