We found a total of 7 inflammatory cytokines with a causal relationship with OLP (Table 1), among which there was a negative correlation between TNFB, IL5 and CX3CL1 with OLP, with the most significant result being TNFB (p=0.00036, odds ratio (OR): 0.960, 95% confidence interval (95%CI): 0.938-0.982). This evidence concerns the gene CX3CL1 and oral lichen planus.