Compared to our study, the autoantibody panel only comprised the following 5 autoantibody tests: anti-thyroid peroxidase (TPO), anti-issue transglutaminase (tTG), anti-CCP, anti-glutamic acid decarboxylase (GADA), and a connective tissue disease (CTD) screening test; borderline and positive CTD tests were further specified into anti-dsDNA, anti-SS-A, anti-SS-B, anti-CENP, anti-Jo-1, anti-Scl-70, anti-Sm, and anti-U1RNP. This evidence concerns the gene TRIM21 and connective tissue disorder.