Here, the autoantibody panel comprised the organ-specific thyroid autoantibodies anti-thyroglobulin (anti-TG) and anti-TPO, the celiac disease-associated anti-tTG and, in case of positive anti-tTG, anti-endomysial autoantibodies (anti-EMA), as well as autoantibodies to the 65-kDa isoform of glutamic acid decarboxylase (anti-GAD65) associated with diabetes. This evidence concerns the gene TPO and diabetes mellitus.