Antisense Non-coding RNA in the INK4 Locus (ANRIL), also known as cell Cycle protein-Dependent Kinase Inhibitor 2B Antisense RNA1 (CDNK2B-AS1), is discovered to be elevated in the renal tissues of people with diabetic nephropathy and has been linked to the development of DN via a variety of pathways (18–22). Here, CDKN2B-AS1 is linked to liver dysplastic nodule.