Plasmacytoma Variant translocation 1 (PVT1) is the first lncRNA suspects to be involved in kidney diseases, and two studies in 2007 reported the role of PVT1 in mediating susceptibility to ESRD caused by type 2 and type 1 diabetes, providing a rationale for PVT1 as a candidate gene for ESRD (45, 46). This evidence concerns the gene PVT1 and kidney disorder.