TGFB1 and neoplasm: They also discovered that CD10 expression is vital for the synthesis of TGF-β1, and its inhibition corresponds with decreased levels of TGF-β1-a tumor suppressor known to curb cell proliferation and induce apoptosis through the upregulation of cell cycle inhibitors (like p21) and the activation of MAP kinases and PI3K/Akt pathways (Mizerska-Kowalska et al., 2021).