MME and Abnormal retinal morphology: As Aβ is believed to have detrimental effects on posterior eye tissues and is implicated in retinal diseases like age-related macular degeneration, Parthasarathy et al. reported in their study that in a mouse model through the intra-vitreal delivery of sNEP (recombinant soluble form of CD10), decreases in ocular Aβ were induced while maintaining good electroretinographic responsiveness in a controlled, dose-dependent manner (Parthasarathy et al., 2015).