Additionally, both Prausmüller et al. and Pavo et al. have demonstrated that the expression levels of membrane CD10 in neutrophils and granulocytes, respectively, are correlated with heart failure prognosis, with lower expression linked to increased severity and higher expression associated with better outcomes (Pavo et al., 2019; Prausmüller et al., 2021). This evidence concerns the gene MME and heart failure.