Notably, molecules exceeding ~60-70 kDa appear to need a cell (e.g., migratory CD103+ cDC1s) to traffic the antigen from peripheral tissues (e.g., tumor) to the TDLN 27,28, thus our use of the relatively small ZsG antigen permits assessment of antigen trafficking via both means. The gene discussed is PATZ1; the disease is neoplasm.