IL9 and B-cell chronic lymphocytic leukemia: P66Shc deficiency in CLL cells impinges on the expression of a number of CLL-critical genes, including genes encoding lymphoid homing receptors, and cytokines such as IL-9 (Capitani et al., 2012; Patrussi et al., 2015; Patrussi et al., 2021a; Tatangelo et al., 2022).