CD8A and familial pancreatic carcinoma: It has been shown that CR3 is expressed on activated CD4+ and CD8+ T cells (Gray and Horwitz, 1988; Savary and Lotzova, 1992; Hamann et al., 1997; Wagner et al., 2001) and a majority of CD8+ TILs from melanoma (Hersey and Jamal, 1990) and pancreatic cancer (Ademmer et al., 1998).