Since then, several reports have confirmed the role of CFH in various solid tumors including glioblastoma (Junnikkala et al., 2000), bone cancer (Fedarko et al., 2000), ovarian cancer (Junnikkala et al., 2002), colon cancer (Wilczek et al., 2008), cutaneous squamous cell carcinoma (Riihila et al., 2014) and breast cancer (Smolag et al., 2020). The gene discussed is CFH; the disease is cutaneous squamous cell carcinoma.