Also, Santos MF et al (Guerra et al., 2022) have found that CD9 interacts with Trop-2 and enhances the growth of colorectal cancer cells through remodeling of β-actin cytoskeleton, proteolytic cleavage of E-cadherin, and activation of Raf-MEK-ERK and PI3K-PDK1-Akt pathways. The gene discussed is CD9; the disease is colorectal cancer.