Two other variants in the same location as MYH7 have been reported (NM_000257.4:c.2342T>C p. Leu781Pro; rs727503259, CM1516000; and NM_000257.4:c.2341C>A p. Leu781Met; rs1348730180, CM1412213) as variants of unknown significance (ClinVar) in patients with hypertrophic cardiomyopathy (HGMD) [PMID:29121657, PMID:28615295]. This evidence concerns the gene MYH7 and hypertrophic cardiomyopathy.