Until now, the Xpert MTB Host response assay [including Dual specificity phosphatase 3 (DUSP3), Guanylate-binding protein (GBP5), Krupple-like factor 2 (KLF2) genes] which was developed by Cepheid (Sunnyvale, CA, United States) has been recommended in TB screening by WHO (Sodersten et al., 2021; Wu et al., 2023). The gene discussed is DUSP3; the disease is tuberculosis.