Until 2020, a study by Li et al. elaborately verified that sepsis‐induced cardiac injury presented close contact with the protein level of NCOA4 and ferritin degradation when H9c2 myofibroblasts were stimulated by lipopolysaccharide (LPS), as evidenced by the expressed level of ferritin significantly decreased with a time dependence whereas NCOA4 expression initiated to be increased upon LPS treatment. Here, NCOA4 is linked to Sepsis.