TCF7L2 and type 2 diabetes mellitus: In addition, one SNP (LOC105369844, rs11180649) was negatively associated with T2D (OR = 0.71, P = 6.70 × 10–6) and two TCF7L2 loci were positively associated (rs7903146 and rs7901695; OR = 1.35 and 1.34 respectively (P < 1 × 10–5)).