One locus in CDKAL1 (rs10946415, OR = 0.71; P = 4.89 × 10–06) and one IGFN1 locus (rs3738270, OR = 0.74; P = 8.16 × 10–06) were negatively associated with T2D. The gene discussed is IGFN1; the disease is type 2 diabetes mellitus.